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It is the most pragmatic thoracic nci national clinical trial network (nctn) trial, with no lab/pft cutoffs, no ct chest/ mri brain/lab time windows, and allowing patients with actionable mutations and ecog ps 2

For protocol amendment 6 to The transfer and update module (t&um) is a new module being developed in the oncology patient enrollment network (open) system Once implemented, it will become the central location requesting and managing institution changes, credentialing data updates, and demographic data updates for completed patient enrollments that are maintained in open. Here we report on the details of the janus rectal cancer trial (the janus trial, nct05610163), a national clinical trials network (nctn) trial testing the optimal tnt regimen using a consolidation chemotherapy approach of triplet versus doublet chemotherapy based on the hypothesis that a triplet chemotherapy regimen after induction lcrt will. No passover will be given in the first five cases in supplementary list”