Most of the best nudity in the substance happens near the beginning of the movie when qualley takes her sweet time checking out her sweet naked body in the mirror after her first transformation Plus we love the looks at iconic milf demi's equally incredible physique at the beginning of the substance. Margaret qualley joked about how her family reacted to her latest film, 'the substance,' during an appearance on 'the tonight show starring jimmy fallon.' The actress daughter of four weddings and a funeral star andie macdowell plays provocative tv aerobics instructor sue in critically acclaimed film the substance. The body horror comedy (it is funny, after all) has been all the talk of social media since it was released this fall — and demi moore's performance as elisabeth sparkle has garnered some. In the substance, elisabeth sparkle (demi moore), a former hollywood star in decline, is fired from her tv show on the very same day as her 50th birthday
After an accident, she discovers a mysterious serum that allows her to create a younger, perfect version of herself, named sue (margaret qualley).
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