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Clinically, it is characterized by skin hyperelasticity and joint hypermobility.

Several types of eds have been identified. Variants in the col5a1 or col5a2 gene, or rarely in the col1a1 gene, can cause the classical type. American journal of medical genetics part c Seminars in medical genetics is an educational resource and review forum for students, practitioners and professionals. Murali gopika manoharan m.d.s and dr Arulraj dental college and hospital, chennai