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For women, the choice of hormone therapy depends on menopausal status and any past hormone treatment for early breast cancer [4].

In addition, the natural dependence on steroid hormone signaling has allowed for therapeutic targeting of this pathway and significant improvements in survival while maintaining quality of life Systemic (drug) treatments for stage iv breast cancer treatment often continues until the cancer starts growing again or until side effects become unacceptable If this happens, other drugs might be tried The types of drugs used for stage iv breast cancer depend on the hormone receptor status, the her2 status of the cancer, and sometimes gene mutations that might be found